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During the fourth quarter and the full year 2025, we achieved notable year-over-year Marketing leverage on both a GAAP and non-GAAP basis, as we benefited from efficiencies related to new product launches, improving organic customer acquisition trends, and steadily improving retention, all of which allowed us to maintain our target payback periods of less than one year

All adverse events were reported from the time of the first dose of liraglutide or placebo to 14 days after the last dose

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Providers use these check-ups to adjust treatment plans as necessary

Subjective improvement in pain, function, and activity tolerance provides the primary effectiveness signal