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58: 53340 Pons R, Carrozzo R, Tein I, et al

In the United States, Medicare coverage for L-carnitine is available for patients who have been on dialysis therapy for at least 3 months, have a plasma free carnitine level less than 40 mol/L, and have erythropoietin-resistant anemiathat has not responded to standard erythropoietin dosageand for which other causes have been investigated and adequately treated. 195 Hyporesponsiveness to ESAs is not specifically defined other than having a persistent Hct less than 30% despite erythropoietin dosage that is considered clinically appropriate to treat the particular patient. The statement There is insufficient evidence to recommend use of L-carnitine in the management of anemia in patients with CKD is supported by results from 6 available RCTs of IV L-carnitine administration to ESA-treated HD patients (Table 32)

Beyond these primary applications, Cartinex stands out for several additional benefits: Weight Management: Aids in weight loss and boosts metabolism

doi: 10.1007/s40265-019-01187-w

Potential for injection site irritation