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Additionally, not many trials meet the clinical design standards to be considered credible

Disruption of the gut microbiota early in life, for instance via antibiotic exposure, can result in long-lasting changes to visceral pain sensitivity and stress responsiveness, as demonstrated in rodent models (O'Mahony et al., 2014

ADP = adenosine diphosphate

The FDA emphasizes that many cases result from unintentional overdoses due to multiple over-the-counter medications containing acetaminophen