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Rotenone as a Parkinson model Rotenone is one of the most studied neurotoxic substances used as a model for PD features and oxidative stress events in cellular and animal models [14,57]

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Mechanistic literature demonstrates that IGF-1 supports satellite cell activation, myogenic differentiation, and regenerative remodeling, which is why IGF-1-linked markers are routinely tracked in preclinical studies involving this combination [7]

The ferroptosis inhibitor Lip-1 functions as a lipophilic antioxidant similar to Fer-1 44

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