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This dual capability positions melatonin as a robust non-enzymatic antioxidant, functioning both intra- and extracellularly [93]

This elevation may be linked to increased fatty acid oxidation associated with wasting/cachexia, as previously observed TB-positive cohorts with depleted fatty acids and free carnitine levels alongside increased medium-chain acylcarnitines (Che et al., 2018

In severe cases, intravenous administration may be considered, but only under medical supervision

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As description indicates in previous work, under conditions with high levels of reactive oxygen molecules, estrogens undergo processing by specific enzymes such as CYP1B1 into forms called 4-hydroxyestrogens that show high reactivity, and these then undergo further oxygen reactions into molecules called quinones