Zaeri S, Emamghoreishi M
The preparation method according to any one of claims 1 to 3, wherein the coupling in the fragmental synthesis of the Lys 26 side chain is performed by condensing with DIC+A or B+A+C until the resin is detected to be transparent with ninhydrin, wherein A is chosen from HOBt or HOAt, B is chosen from HBTU, HATU, TBTU, PyAOP, or PyBOP, C is chosen from DIPEA or TMP
Contact your GP or diabetes specialist nurse if hiccups persist for more than 48 hours, interfere with eating or sleeping, or occur alongside concerning symptoms such as severe abdominal pain, chest pain, or difficulty breathing
However, if it is used at very high doses over long periods, it can cause nerve damage (neuropathy)
They are also an excellent choice for those who may forget daily pills
Patients can use tirzepatide less frequently than every seven days