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This dual action of promoting both MMP-2 and TIMPs might appear contradictory

Studies have reported that among SCFAs, butyrate alone is responsible for gut motility, possibly via regulating serotonin, and can be used to increase propulsive gut movement, making it a suitable microbial therapeutic for patients with IBS (Vincent et al., 2018)

Compounding quality is not FDA-verified: Compounded products are not reviewed for potency, sterility or purity before dispensing, so provenance from a reputable 503A/503B pharmacy materially affects the safety profile [8]

doi:10.2105/AJPH.2016.303299

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Among them, butyrate has been considered of significant importance, as it is involved in several functions of physiological importance, such as trans-epithelial transport, amelioration of mucosal inflammation, alleviation of oxidative stress, enforcement of the epithelial barrier, and protection against colorectal cancer (CRC) (Hamer et al., 2008)