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Similar to the BPC 157 effect on sphincters function, BPC 157 exhibited a particular anti-reflux effect in healthy (i.e., increase of pressure within lower esophageal sphincter, decrease of pressure within pyloric sphincter), while also rescuing sphincters failure (i.e., decreased pressure) in esophagitis rats (increase toward the normal values) (31, 32)

the capacity of HGF to induce new synaptic connections and stimulate neurogenesis in the hippocampus supports the use of HGF mimetics for the treatment of depression

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The approaches adopted in these traditions often emphasize dietary regulation, the use of polyherbal formulations, seasonal detoxification, and the balance of internal energies or humors, aligning with modern understandings of the gut as a complex, integrative organ with profound systemic influence