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This "energy sink" literally starves the brain, heart, and skeletal muscles of energy, directly causing the hallmark symptom of post-exertional malaise (PEM) and the severe exercise intolerance seen in these conditions

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On admission day, patients underwent an interview including questions on alcohol consumption such as daily quantity and type of alcohol (beer, wine, liquor/distilled spirits) and age at onset of alcohol use

Furthermore, expression of pro-apoptotic and anti-apoptotic proteins is variable during individual stages of erythropoiesis, which determines apoptosis susceptibility at each stage of differentiation

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