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Dietary assessment for weight management and health maintenance

When protein hits your gut, it stimulates your L-cells to release GLP-1 more powerfully than any other macronutrient

How these medications cause weight loss when combined is still somewhat of a mystery, but experts theorize that the combo touches the brains reward centers: Bupropion affects the pathways of two neurotransmitters, dopamine and norepinephrine, which are used in brain areas that process appetite and reward, and naltrexone tends to boost and reinforce this effect, Maselli says

MRI-based research has also confirmed reduced food cravings and altered reward responses in the brain with semaglutide use

Sakata, K

GLP-1 is produced by specific cells located in the intestines as a result of food intake