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Since BBB breakdown and vascular dysfunction are a hallmark of AD, therapeutics targeting the BBB are of great potential [136]

For Dapagliflozin 21 pregnancies were reported of which 8 listed the corresponding pregnancy outcomes: 1 congenital hydrocephalus, 2 encephalocele, 1 non-healthy infant with talipes, renal aplasia and oesophageal atresia, 2 induced abortions, 1 healthy premature infant, 1 healthy infant

Tirzepatide's ongoing SURPASS-CVOT trial will provide similar data

Preventing Constipation Because GLP-1s slow down the digestive tract, constipation is a frequent challenge

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