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"Pivalate-generating prodrugs and carnitine homeostasis." Pharmacol Rev 2002;54:589-98
For example, the activation of the rate-limiting enzyme HMG-CoA reductase (HMGCR) in cholesterol biosynthesis shows circadian rhythm ( + biosynthesis (Ramsey et al., 2009)
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As a dual agonist, it targets both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
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