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Peptides were eluted over 60 min using a binary buffer system consisting of buffer A (0.1% formic acid) and buffer B (80% ACN, 0.1% formic acid)

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The published evidence base for CJC-1295 Without DAC draws on both the direct characterisation of the tetrasubstituted backbone and the extensive clinical and pre-clinical literature generated for CJC-1295 with DAC, which shares the same four amino acid substitutions and GHRH receptor pharmacology

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Dose increases typically occur every 4 weeks, following the clinical trial schedule

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