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Comprehensive review of the hormone GLP-1 including its effects on multiple aspects of human health and the use of GLP-1 R agonists in type 2 diabetes and obesity

Studies show that stopping GLP-1 therapy typically results in gradual weight regain over 6-12 months, though most patients maintain at least 50% of their initial weight loss if they continue the lifestyle changes learned during treatment

An mTOR paradox in sarcopenia via BCAA catabolism