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By attaching to GLP-1 receptors on these structures, GLP-1RAs decrease dopamine release and therefore make addictive behaviors less rewarding

Despite the promising results, the glucose-responsiveness of these IPC remains limited

70 Of note is that the benefits of this agent were shown both in diabetic and non-diabetic patients

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Behavioral adherence enhances outcomes

Weak Effects in Chronic Insomnia A 1992 study reported higher sleep efficiency and shorter sleep latency relative to placebo