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reported that participants in the CR combined with exercise group experienced significantly higher rates of hip fractures (10 per 10 000 person-years) compared to controls (6 per 10 000 person-years)

Side effects: Primarily gastrointestinalnausea, vomiting, diarrhea, and constipationwhich are generally mildtomoderate and transient [4] [5]

NHS availability would require successful Phase 3 trials, marketing authorisation, and a positive NICE health technology appraisal

This can lead to weight loss that is primarily fat, not muscle

Common Side Effects: Like any medication, GLP-1 analogues may cause certain side effects, although they are generally well-tolerated by most individuals