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354 GLP-1RAs and musculoskeletal health GLP-1RAs and bone The quality of bone depends on bone metabolism, and the main factors affecting bone metabolism include osteoclasts, osteoblasts, and calcitonin

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Bliddal H, Leeds AR, Christensen R (2014) Osteoarthritis, obesity and weight loss: evidence, hypotheses and horizons - a scoping review

It appears to represent a recalibration of the brain's reward and satiety circuitry, reducing the hedonic drive to eat independently of hunger signals

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