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Copley SD, Dhillon JK: Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes

An article cited in Journal of Cancer Science and Therapy indicated that glutathione deficiency leads to increased levels of oxidative stress, which might lead to cancer.

These studies suggest that subcellular compartmentalization of GSH, rather than total cellular GSH abundance alone, is a critical determinant of apoptotic sensitivity

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