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Long-term use can lead to sustained weight loss and improvements in overall metabolic health

NHS access for either, once licensed, would hinge on a NICE technology appraisal after MHRA approval

By combining genetic context with clinical biomarkers (metabolic rate, body composition, hormonal markers), you and your provider can move beyond one-size-fits-all maintenance advice

Both drugs require careful dose escalation or clinical monitoring to manage these effects safely

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