In laboratory and pre-clinical settings, AOD9604 has been studied across several distinct biological systems
This results in dramatically enhanced uptake, with a much higher proportion of free, active peptide available for receptor interaction
10.1111/nph.16086 New Phytol
#extracellularvesicles #exosomes #EVisolation #Vesiculab Roberto Frigerio's Membrane-Sensing Peptide uEV Isolation Method Optimizing urinary extracellular vesicle isolation using membrane-sensing peptides: in this preprint article, Roberto Frigerio at ETH Zrich, Adele Tanzi at Universit degli Studi di Torino and collaborators employed a membrane-sensing peptide (MSP)-based affinity capture strategy for urinary extracellular vesicle (uEV) isolation that exploited the high membrane curvature characteristic of EVs, enabling broad, marker-independent vesicle capture
10.3389/fimmu.2024.1435139 72 LuQ.ShaoN.FangZ.OuyangZ.ShenY.YangR.et al (2025)
This controlled release mechanism helps avoid desensitization of the pituitary glands receptors over time, ensuring sustained effectiveness of the peptide