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Glutathione is a master antioxidant (scavenging free radicals),inflammatory regulator, and immune system powerhouse

Hierarchical clustering was performed using the Morpheus Software ( with the Pearson correlation and average linkage method

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The current study addressed these limitations by testing a noninvasive nasal GSH repletion strategy, and measuring CNS uptake via proton magnetic resonance spectroscopy ( 1 H-MRS)

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Given NR3C1s central role in HPA axis regulation and its known involvement in depression, such epigenetic dysregulation may represent a shared vulnerability mechanism across addiction and mood disorders