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The most common gene mutations are BRCA1 and BRCA2

Recent studies indicate that after a single dose of UA, mice metabolize it rapidly within 3 h, producing three types of phase II metabolites: UA-3-O-glucuronide, UA-3-sulfate, and UA-sulfate glucuronide (20)

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Durand E, Laguerre M, Bourlieu-Lacanal C, Lecomte J, Villeneuve P

pre-planned contrasts between times were inserted in the model

Some mutations accelerate intestinal tumor formation, 210 while MT-CYTB and MT-CO1 variants enhance tumor growth through ROS-induced NF-B2 activation