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Blood-Brain Barrier (BBB) Vulnerability: The BBB protects the brain from harmful substances in the bloodstream but can also limit the delivery of antioxidants and other protective agents to the brain

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Fu JM, Satterstrom FK, Peng M, Brand H, Collins RL, Dong S, et al

And you would never know the difference by looking at the vial, because most degradation happens at the molecular level, invisible to the naked eye

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