To address the role of GLP-1 in the NAc, the same group investigated how Ex4 affects the activity of NAc MSNs (Mietlicki-Baase et al., 2014)
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Additional important metabolic regulatory enzymes that require flavin as a co-factor include, succinate dehydrogenase (TCA cycle and complex II of oxidative phosphorylation), glycerol-3-phosphate dehydrogenase (involved in the glycerol phosphate shuttle and triglyceride synthesis), and xanthine oxidase involved in purine nucleotide catabolism
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PlexusDx patients achieve comparable weight-loss outcomes to Ozempic users at a fraction of the cost