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Inhibition of IGF-IR impairs the repair of radiation-induced double strand breaks and sensitizes cancer cells to radiotherapy [82]

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At higher doses it can cause confusion, vomiting, respiratory depression, and abrupt coma

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Se evalu la farmacocintica de semaglutida en pacientes con insuficiencia renal leve, moderada o grave y en pacientes con enfermedad renal terminal en dilisis en comparacin con personas con una funcin renal normal en un estudio en el que se administraba durante 10 das consecutivos semaglutida una vez al da