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These compounds sit in a gray zone: they are legal to sell and own for laboratory research, but they are not approved by the FDA for human use and are not dietary supplements

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This could potentially limit its use in human medicine

Another important facet to consider for the limited activity of angiogenesis inhibitors in breast cancer is the population under examination to allow the identification of breast cancer patients who would benefit most from anti-angiogenic drugs

This leads to a lower calorie intake, which can help with weight loss

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