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Clinicians prescribing BPC-157 should document the following in the medical record: the off-label nature of the prescription, the absence of human clinical trial data, the FDA's position on compounded BPC-157, the patient's prior treatment history with approved therapies, and the patient's written informed consent

Published validation flags REM as its weakest stage (21-min discrepancy vs PSG)

On appearance, they look as they always have done

Despite the existence of such a simple treatment, doctors in the USA, UK, and other countries consistently deny it to patients with B12 deficiency and pernicious anemia

Kawasaki and Kawai, 2014