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Specifically, OUD patients receiving Ozempic have a 54% lower risk of opioid overdose than those taking metformin, a 58% lower risk than insulin alone, a 63% lower risk compared to DPP-4i, and a 42% low risk compared to SGLT2i

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These mechanisms seem to be, at least in part, mediated through the modulation of the growth hormone/IGF-1/insulin system

They include age at diagnosis, how far the disease has progressed at diagnosis, and whether individuals have other health conditions that may shorten lifespan or complicate care