These impacts include increasing neuron progenitor cells proliferation, prolonging potentiation in the hippocampus, improving learning, as well as reducing plaque formation and inflammation in the brain (73)
While possible, maintaining results after stopping GLP-1 therapy is challenging and requires intensive lifestyle modifications including 200-300 minutes of weekly exercise, consistent dietary changes, regular self-monitoring, and often ongoing behavioral support
The most commonly reported adverse effects were gastrointestinal nausea, vomiting, diarrhoea, and constipation consistent with the GLP-1 receptor agonist class and generally dose-dependent
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