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Testing the affected patient first is the most informative strategy for relatives

The majority of the data remain preclinical

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Previous studies have indicated that the association between DM and AF may involve mechanisms such as oxidative stress, inflammatory responses, abnormal energy metabolism, impaired cellular calcium handling, dysfunctional ion channels, and conduction disturbances (55)

[1] [2] While injection-site reactions are classified as uncommon in the official product information, bruising can occur at the injection site