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Women following the retatrutide dose schedule may benefit from planning dose escalations to avoid the luteal phase of their menstrual cycle, when GI sensitivity tends to be highest
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GLP-1 stimulates the release of insulin in the pancreas after eating, especially when blood sugar is elevated
GLP-1 receptors sit in the pancreas (driving glucose-dependent insulin secretion and suppressing glucagon), in the hypothalamus (appetite suppression and satiety), in the GI tract (slowed gastric emptying), and on cardiomyocytes in the heart
In sommige situaties kan een arts besluiten semaglutide off-label voor te schrijven bij overgewicht
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