Calcineurin is a transcription factor that is essential for the activation of nuclear factor of activated T-cells (NFAT), which is responsible for the production of pro-inflammatory cytokines, including IL-1, IL-2, IL-6, IL-4, and interferon (IFN)- (Pandey et al
g , LX293T cells expressing HA-tagged KRAS G13D were treated with STR (250 nM) or SHP099 (500 nM), and RMC-7977 with indicated concentration for 2 h followed by HA-pulldown and CYPA immunoblot
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Bazinet RP, Weis MT, Rapoport SI, Rosenberger TA
Mou Y, Wang J, Wu J, He D, Zhang C, Duan C, et al
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