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Since this 2012 publication, there has been very little new research into this question

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Thats where vitamin B12 injections come in

Dietary choices play a major role in developing varicose veins with poor nutritional choices and deficiencies worsening vein damage and hampering blood circulation

Gather supplies: Assemble the following supplies: needle and syringe with medication or an auto-injector pen alcohol pads gauze puncture-resistant container to discard the used needles and syringe (typically a red plastic sharps container) bandages Inspect the injection site: Before injecting medication, inspect your skin to make sure theres no bruising, burns, swelling, hardness, or irritation in the area