City: Ottawa: Ottawa Health Research Institute Moretti P, Sahoo T, Hyland K, Bottiglieri R, Peters SU, Del Gaudio D, Roa B, Curry S, Zhu H, Finnell RH: Cerebral folate deficiency with developmental delay, autism and response to folinic acid
Increased ER stress by depletion of PDIA6 impairs primary ciliogenesis and enhances sensitivity to ferroptosis in kidney cells
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A spinoff company, Athira Pharma (formalized as M3 Biotechnology before rebranding), was founded in 2011 by PhD student Leen Kawas to commercialize dihexa and a related molecule, ATH-1017 (fosgonimeton)
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Second, many of the mechanisms discussedincluding cellular senescence, inflammaging, sarcopenia, and endocrine declineare well-established hallmarks of aging but are not specific to diabetes