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This is further supported by observations that the frequent oligoclonal immunoglobulins produced behind the blood brain barrier in MS may be non-specific, targeting general cellular debris (Brndle et al., 2016

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So the research is kind of scratching the head off

FDA reviewers cited limited human clinical evidence and unresolved safety concerns, and the agency will make the final decision

The body can do this but many times the reason the deficiency exists is because there is some venerability with formation of methyldonors (like methylcobalmin)

Editor: Hagai Ginsburg, The Hebrew University of Jerusalem, Israel Received: May 8, 2013