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67 In 2018, a meta-analysis of four RCTs found significant benefits for herpetic neuralgia of locally injected methyl-B12, 1 mg on 6 days per week for 24 weeks
However, on July 23-24, 2026, the FDAs Pharmacy Compounding Advisory Committee (PCAC) voted on inclusion of two of GLOWs peptide compounds for the 503A Bulks List: BPC-157 : 8-6 voted in favor of inclusion, with one abstention TB-500 : 8-6 voted in favor of inclusion, with one abstention Note: TB-500 is a fragment of the full-length thymosin beta-4 (43 amino acids)
Injectable routes carry a particular concern for immunogenicity from peptide aggregation and impurities, and FDA noted the available certificates of analysis for AOD-9604 bulk drug substances did not consistently control for impurities, aggregates, or microbial limits
This method bypasses the digestive system that can compromise absorption
Does that help the pain