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Highlights This study systematically expounded the main mechanism of action of Ganoderma lucidum polysaccharides in treating diabetic complications

Peptides modulate tissue repair pathways over weeks they do not provide immediate symptomatic relief or address mechanical factors like straining or venous congestion

The effects of melatonin on endometriotic lesions induced by implanting human endometriotic cells in the first SCID-mouse endometriosis-model developed in Turkey

Niacinamide and GHK-Cu help reduce inflammation and improve tolerance over time

Research-Use Framework Under the Food and Drugs Act Research-grade peptides fall outside the prescription drug authorization scope when supplied for in vitro laboratory work, but the framework places compliance responsibility on the purchasing institution

NR-S: Investigation, Methodology, Writing review and editing