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YTHDF1 knockdown significantly increased the survival rate of KGN cells, but SLC7A5 overexpression effectively attenuated this protective effect (Fig

3e), suggesting an engagement with -cells that is consistent with activity at both the GIPR and GLP-1R 35,36

Clinical trials have demonstrated impressive results with Tirzepatide/Mounjaro, showing significant reductions in body weight and improvements in metabolic parameters such as blood sugar levels and cholesterol levels

doi:10.1038/sj.jid.5700289

And many people are surprised by this because they think surgery must be so much more expensive than GLP-1s

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