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Commonly prescribed GLP-1 medications in the UK include semaglutide (Ozempic, Wegovy, Rybelsus), dulaglutide (Trulicity), liraglutide (Victoza, Saxenda), and exenatide products

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Native human GLP-1 has a very short half-life of approximately 2 minutes due to rapid degradation primarily by the enzyme dipeptidyl peptidase-4 (DPP-4), with neutral endopeptidase (NEP) also contributing to its breakdown

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