If side effects persist, your provider may recommend adjusting your dosing schedule or switching to a different formulation
Some of the most common or potential side effects include: Nausea Constipation Vomiting Diarrhea Abdominal pain Headache Indigestion Injection site reactions Dizziness Back pain Increased lipase or amylase Altered taste Nasopharyngitis (common cold) Passing gas Bloating Belching Gastroenteritis Decreased appetite Fatigue Gastroesophageal reflux disease Low blood sugar (hypoglycemia) in those with Type 2 diabetes Upset stomach These symptoms often subside as your body adjusts to the medications
Why Weight Loss is Challenging
Among Cleveland Clinics 83,000 employees worldwide are more than 6,600 salaried physicians and researchers, and 21,900 registered nurses and advanced practice providers, representing 140 medical specialties and subspecialties
In May 2026, the Centers for Medicare & Medicaid Services (CMS) announced a major new effort to improve access to high-cost weight-loss medications for older Americans
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