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Symptom-free at first, she lost 30 pounds
Some research has shown that GLP-1s may cause gastroparesis, or stomach paralysis, in some people
When GLP-1 use is continued, weight reduction is sustained for at least 4 years in controlled and observational studies [17]
The most common GLP-1 side effects are gastrointestinal symptoms: nausea, vomiting, diarrhea, and constipation
Phase 2 trial data (NEJM, 2023) reported a mean body weight reduction of approximately 24% over 48 weeks at the highest dose, though larger Phase 3 trials are needed to confirm these findings
GLP-1 drugs prompt the pancreas to release more insulin while suppressing glucagon, a hormone that raises blood sugar, according to the Cleveland Clinic
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