kim kardashian glp-1 on Losing Weight to Wear Marilyn Monroe Dress to Met Gala Kris Jenner says GLP-1 drugs

Over a year, that 60-100 calorie daily deficit represents 6-10 pounds of potential weight loss or, conversely, 6-10 pounds of easier weight regain during a drug holiday

Effects on Reward Circuits One of the most intriguing findings is GLP-1s interaction with the brains mesolimbic reward system

In this post: The science Why Weight Regain Happens After Stopping GLP-1s What are your options if you have reached your target BMI with GLP-1 medications

Track your metrics weekly but evaluate progress monthly

This approach represents a fundamental shift from the conventional more is better mentality in medicine

Back Mller, TD, Blher, M, Tschp, M, DiMarchi, iRD (2022) 'Anti-obesity drug discovery: advances and challenges', Nature Review Drug Discovery , 21, 201-23