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GLP-1(936) also exerted a glucagonostatic effect at 6 mmol/l glucose but not at 20 mmol/l glucose
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That being said, the standard weight loss recommendation for anyone living with diabetes or obesity is 7 to 10 percent of your body weight, which means metformin can certainly help you get there when its combined with supportive lifestyle habits. Just like Ozempic and other GLP-1 medications making headlines, you have to commit to making real changes in how you eat and exercise every single day, emphasized Jose
More important than my observation is the following: In comments by Thompson and Sturmer published in the journal Diabetes Care in 2023, about a study of GLP-1s and the risk of thyroid cancer conducted by Bezin et al which was published in the same journal issue, Thompson and Sturmer conclude that Thyroid cancer is a rare outcome, however, and the potential increase in absolute risk is very small
Thyroid concerns: Animal studies showed thyroid tumors with both medications
When you activate this receptor too aggressively, nausea, vomiting, and diarrhea become significant problems
