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Maybe a combined approach, where you're reducing the pain through weight management, but you're also trying to regenerate the cartilage, is the way to go in the future.

The strength training preserved muscle mass and boosted metabolism, while food tracking ensured proper nutrition to support workouts

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This creates a positive feedback loop: more fiber leads to more SCFA, which promotes more GLP-1, supporting blood sugar and appetite regulation (Mozafariun et al 2025

The role of AMPK in macrophage metabolism, function and polarisation

Because GLP-1 receptors are also present in reproductive tissue, these medications have shown promise in improving symptoms, with a survey of 161 women supporting this