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It increases the risk for multiple metabolic complications including type 2 diabetes (T2D), metabolic-dysfunction associated steatotic liver disease (MASLD, previously known as non-alcoholic fatty liver disease), cardiovascular disease as well as many mechanical complications such as osteoarthritis and obstructive sleep apnoea (OSA) [3]

Process of maturation to Pro-IGF- requires glucose regulating protein 94 (GRP94) that possesses chaperone activity towards IGF-I

Aging 21 (2), 183197

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Silymarin & Glutathione are antioxidants that protect against oxidative stress and neutralize hepatotoxicity

CNS Drugs 28:743752 Addolorato G, Leggio L (2010) Safety and efficacy of baclofen in the treatment of alcohol-dependent patients