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Diet-induced ketosis increases capillary density without altered blood flow in rat brain

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201,202 Over the past decade, numerous studies have found that dysbiosis affects the occurrence and development of digestive system diseases

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It was suggested that MO improved endothelium relaxation by increasing Akt signaling, activating endothelial NO synthase and down-regulating arginase-1 ( 4.3 Ameliorative Effects of MO in Cardiac Toxicity Condition/Myocardial Infarction Various studies have evaluated numerous natural products that might have cardioprotective effects by using different methods in animal models, such as surgery or drug-induced cardiotoxicity methods, to mimic human myocardial infarction (MI) ( A study using specific alkaloid from MO leaves, N,-L-rhamnopyranosyl vincosamide (VR), for the pretreatment of ISO-induced cardiotoxicity in rat models with a dose of 40 mg/kg BW orally for 7 days showed inhibition of the ST-segment elevation, normal heart rate, and decrease of necrotic cells of cardiac muscle ( in vitro and in vivo

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