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Little or no tumor specificity, poor tumor penetration, cancer cell heterogeneity, insufficient drug accumulation into the tumors abound with the development of multidrug resistance (MDR) conferred by many factors, and finally, undesirable side effects are all crucial matters that contribute to the lack of effectiveness and eventually therapeutic failure observed in conventional cancer therapeutics

The issue is relative impact

Additionally, the weight loss many patients experience can have positive effects on sexual health

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This question is becoming increasingly relevant as clinicians observe patients benefiting from GLP-1 therapy even without significant weight loss