In Phase 3 TRIUMPH-1 (May 21, 2026), the 12 mg arm averaged 28.3% weight loss at 80 weeks, and a higher-BMI subgroup reached 30.3% at 104 weeks
That's roughly 2-3% more weight loss than tirzepatide and 9% more than semaglutide at their respective maximum doses
Through Polly, you can access independent medical providers who evaluate your eligibility and, if medically appropriate, recommend treatment plans that may include prescription medication delivered straight to your door

specializing in weight management, GLP-1 medication nutrition therapy, bariatric surgery, digestive health, and sustainable behavior change Leah Jones, MD Board-certified in Internal Medicine and Obesity Medicine Leah Jones, MD Board-certified in Internal Medicine and Obesity Medicine Katherine Austin, MD, MPH, FAAP, FRCP(C) Board-certified in Pediatrics and Adolescent Medicine Katherine Austin, MD, MPH, FAAP, FRCP(C) Board-certified in Pediatrics and Adolescent Medicine Heather Cecchini, MSN, APRN, ANP-C Board-certified Adult-Primary Care Nurse Practitioner Heather Cecchini, MSN, APRN, ANP-C Board-certified Adult-Primary Care Nurse Practitioner Clete Barrick, MD Board-certified in Internal Medicine and Obesity Medicine Clete Barrick, MD Board-certified in Internal Medicine and Obesity Medicine Caitlin Camill, RDN, CDCES Certified Diabetes Care and Education Specialist
Give yourself a break I tell every single one of my patients this: youre dealing with a complex medical condition
On the operations side, prompt cashier updates and automated status notices reduce guesswork, while detailed help-center articles spare you from waiting in a queue for routine answers