Neuroscience 252:320325
(1) Adolescence (1218 years): high sensitivity to high-sugar diets Although human studies investigating the gut microbiome in adolescents remain limited, the ongoing development of the gut-brain axis and the adolescent brain suggests that this population may be particularly susceptible to diet-induced depressive symptoms (320), The impact of high-sugar diets on metabolic and intestinal health In male C57BL/6J mice, consumption of a high-glucose diet (HGD) over a 12-week period induces hyperglycemia, glucose intolerance, dyslipidemia, and increased adipose deposition
Neurosci Lett 299:113116 Lindenau J, Noack H, Asayama K, Wolf G (1998) Enhanced cellular glutathione peroxidase immunoreactivity in activated astrocytes and in microglia during excitotoxin induced neurodegeneration
Indeed, the basal oxygen consumption rate (OCR) of Gclc -deficient FoB measured by extracellular flux analysis was slightly reduced compared to Gclc fl/fl FoB (Fig
References Lee S, Jo K, Jeong SK, Choi YS, Jung S
Growth hormone replacement therapy prevents sarcopenia by a dual mechanism: improvement of protein balance and of antioxidant defenses