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doi:10.1038/nrn1703

A first step towards standardizing OCT measurements for monitoring MS disease progression in all age groups was made in a study published in 2024, in which age-adjusted z scores for RNFL and ganglion cell/inner plexiform layer thickness were established from reference data and used for individualized prediction of MS disease activity 79

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[DOI] [PMC free article] [PubMed] [Google Scholar] 20.Rhee S.G., Bae Y.S., Lee S.R., Kwon J

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To minimize gastrointestinal side effects, the tirzepatide dose was gradually increased in all SURMOUNT clinical trials, starting at 2.5 mg and escalating by 2.5 mg every 4 weeks until reaching the maintenance dose required